Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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xerC-2Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (442 aa)    
Predicted Functional Partners:
rpmE2
COGs: COG0254 Ribosomal protein L31; InterPro IPR002150; KEGG: rsl:RPSI07_2195 50S ribosomal protein L31, type B subfamily; PFAM: ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: ribosomal protein L31; PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31.
  
 
 
 0.700
Isop_1189
Cell division protein FtsK/SpoIIIE; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593: IPR002543: IPR018541; KEGG: psl:Psta_2807 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: Cell divisionFtsK/SpoIIIE; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
 
   
 0.647
Isop_1810
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: dau:Daud_1182 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
  
    0.627
rpsU
SSU ribosomal protein S21P; InterPro IPR001911; KEGG: psl:Psta_3640 ribosomal protein S21; PFAM: ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
   
 
 0.626
Isop_0196
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: cja:CJA_0425 competence protein ComF; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
   
    0.624
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.620
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.616
rpsJ
SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
    
 
 0.610
rpsI
COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: eba:ebA937 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
    
 
 0.608
rpmG
LSU ribosomal protein L33P; InterPro IPR001705; KEGG: plm:Plim_0436 ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family.
    
 
 0.598
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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