STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_3005COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: plm:Plim_0864 molybdopterin biosynthesis MoaE protein; PFAM: molybdopterin biosynthesis MoaE protein; SPTR: Molybdopterin converting factor (Subunit 2); PFAM: MoaE protein. (171 aa)    
Predicted Functional Partners:
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 
 0.987
moaC
GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 
 0.980
Isop_2632
Molybdopterin converting factor, subunit 1; InterPro IPR003749: IPR010034; KEGG: psl:Psta_2343 thiamineS protein; PFAM: thiamineS protein; SPTR: ThiamineS protein; TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal.
 
 
 0.966
Isop_1375
thiamineS protein; InterPro IPR003749; KEGG: tfu:Tfu_2369 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: ThiS family.
  
 
 0.929
Isop_1376
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: sti:Sthe_0801 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: Molybdopterin biosynthesis protein MoeB; PFAM: MoeZ/MoeB domain; ThiF family.
 
 0.915
Isop_1342
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594; KEGG: psl:Psta_4146 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family.
 
 0.861
Isop_1676
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR008284: IPR020817: IPR001453; KEGG: pca:Pcar_2074 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor biosynthesis mog; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
 
 
 0.848
Isop_3431
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.822
Isop_1255
Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.807
Isop_1559
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.802
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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