STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3033Redoxin domain protein; InterPro IPR017937: IPR017936: IPR013740; KEGG: rru:Rru_A0398 thiol-disulfide isomerase and thioredoxins-like; PFAM: Redoxin domain protein; SPTR: Thiol-disulfide isomerase and thioredoxins-like; PFAM: Redoxin. (966 aa)    
Predicted Functional Partners:
Isop_1414
Redoxin domain protein; InterPro IPR017936: IPR013740: IPR017937; KEGG: mch:Mchl_0201 redoxin domain protein; PFAM: Redoxin domain protein; SPTR: Redoxin domain protein; PFAM: Redoxin.
  
     0.749
Isop_0616
Redoxin domain protein; InterPro IPR013740: IPR017936: IPR017937; KEGG: mch:Mchl_0201 redoxin domain protein; PFAM: Redoxin domain protein; SPTR: Redoxin domain protein; PFAM: Redoxin.
  
     0.680
Isop_0047
Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR017936; KEGG: plm:Plim_0535 cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region; Protein of unknown function, DUF255.
 
 
 0.653
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.515
Isop_1993
InterPro IPR000866: IPR017936; KEGG: rpf:Rpic12D_3102 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen.
  
     0.500
Isop_3032
KEGG: npu:Npun_R2871 hypothetical protein; SPTR: Phosphoribosylaminoimidazole synthetase.
       0.484
Isop_2670
NAD-dependent formate dehydrogenase flavoprotein subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: mno:Mnod_8359 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F [...]
   
   0.471
Isop_3157
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: kfl:Kfla_2118 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase- [...]
   
   0.471
Isop_0662
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG1999 Uncharacterized protein SCO1/SenC/PrrC involved in biogenesis of respiratory and photosynthetic systems; InterPro IPR000866: IPR017936; KEGG: aba:Acid345_3047 electron transport protein SCO1/SenC; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Electron transport protein SCO1/SenC; PFAM: Copper binding periplasmic protein CusF; SCO1/SenC.
  
   0.467
Isop_0868
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 
 0.416
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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