Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3039Capsular exopolysaccharide family; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR005702: IPR003856; KEGG: rmr:Rmar_1126 capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein; PRIAM: Non-specific protein-tyrosine kinase; SPTR: Capsular exopolysaccharide family; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family. (826 aa)    
Predicted Functional Partners:
Isop_0221
Soluble ligand binding domain protein; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR019554; KEGG: rba:RB754 polysaccharide export protein; PFAM: Soluble ligand binding domain; SPTR: Wza; PFAM: Polysaccharide biosynthesis/export protein; SLBB domain.
 
 
 0.959
Isop_1082
Polysaccharide export protein; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715; KEGG: rba:RB754 polysaccharide export protein; PFAM: polysaccharide export protein; SPTR: Probable polysaccharide export protein; PFAM: Polysaccharide biosynthesis/export protein.
 
 
 0.947
Isop_3192
COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: gme:Gmet_2031 sugar transferase; PFAM: sugar transferase; SPTR: Sugar transferase, PEP-CTERM system associated; PFAM: Bacterial sugar transferase.
 
  
 0.894
Isop_0923
COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: cyb:CYB_1783 sugar transferase family protein; PFAM: sugar transferase; SPTR: Bacterial sugar transferase family protein; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
 
  
 0.892
Isop_3040
Hypothetical protein; KEGG: mxa:MXAN_1052 O-antigen polymerase family protein; SPTR: O-antigen polymerase family protein.
  
  
 0.728
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.679
Isop_0054
Multi antimicrobial extrusion protein MatE; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002528; KEGG: gbm:Gbem_1791 polysaccharide biosynthesis protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein.
 
  
 0.635
Isop_2670
NAD-dependent formate dehydrogenase flavoprotein subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: mno:Mnod_8359 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F [...]
     
 0.613
Isop_3157
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: kfl:Kfla_2118 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase- [...]
     
 0.613
Isop_3129
Capsular exopolysaccharide family; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR005702: IPR003856; KEGG: rce:RC1_4006 succinoglycan biosynthesis transport protein ExoP; PFAM: lipopolysaccharide biosynthesis protein; SPTR: Putative uncharacterized protein; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family.
 
  
0.589
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.