Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_3042Eight transmembrane protein EpsH; InterPro IPR013426: IPR019127; KEGG: dvl:Dvul_3054 eight transmembrane protein EpsH; PFAM: Exosortase EpsH-related; SPTR: Eight transmembrane protein EpsH; TIGRFAM: eight transmembrane protein EpsH; PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: eight transmembrane protein EpsH (proposed exosortase). (402 aa)    
Predicted Functional Partners:
atpE
H+transporting two-sector ATPase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 0.939
Isop_3043
EpsI family protein; InterPro IPR014263; KEGG: dba:Dbac_2581 EpsI family protein; SPTR: EpsI family protein; TIGRFAM: EpsI family protein; PFAM: Protein of unknown function (DUF3485); TIGRFAM: EpsI family protein.
 
     0.929
Isop_1097
InterPro IPR014346: IPR003675; KEGG: amr:AM1_1967 CAAX prenyl protease-related protein, putative; PFAM: Abortive infection protein; SPTR: Caax prenyl protease-related protein, putative; TIGRFAM: CAAX prenyl protease-related protein; PFAM: CAAX amino terminal protease family; TIGRFAM: CAAX prenyl protease-related protein.
  
     0.698
Isop_2239
Exosortase EpsH-related protein; InterPro IPR019127; KEGG: rba:RB2461 hypothetical protein; PFAM: Exosortase EpsH-related; SPTR: Putative uncharacterized protein; PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: eight transmembrane protein EpsH (proposed exosortase).
  
     0.663
Isop_3155
COGs: COG3424 naringenin-chalcone synthase; InterPro IPR011141: IPR001099: IPR012328; KEGG: syw:SYNW0993 putative chalcone synthase; PFAM: chalcone and stilbene synthase domain protein; PRIAM: Naringenin-chalcone synthase; SPTR: Chalcone synthase (CHS); PFAM: Chalcone and stilbene synthases, N-terminal domain; Chalcone and stilbene synthases, C-terminal domain.
    
  0.633
Isop_3506
KEGG: gox:GOX1189 hypothetical protein; SPTR: Putative uncharacterized protein.
    
   0.593
Isop_0221
Soluble ligand binding domain protein; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR019554; KEGG: rba:RB754 polysaccharide export protein; PFAM: Soluble ligand binding domain; SPTR: Wza; PFAM: Polysaccharide biosynthesis/export protein; SLBB domain.
 
     0.589
Isop_1326
Hypothetical protein; KEGG: gsu:GSU1537 general secretion pathway protein-related protein; SPTR: General secretion pathway protein-related protein.
 
    0.587
Isop_2238
InterPro IPR019734: IPR001440: IPR013026; KEGG: ade:Adeh_3311 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR domain protein.
 
     0.585
Isop_3197
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sus:Acid_0271 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase, group 1; PFAM: Glycosyl transferases group 1.
  
     0.566
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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