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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3045KEGG: dsh:Dshi_1950 hypothetical protein; SPTR: Putative uncharacterized protein. (195 aa)    
Predicted Functional Partners:
Isop_0290
COGs: COG3379 conserved hypothetical protein; InterPro IPR001917: IPR002591; KEGG: hoh:Hoch_2285 type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
 
     0.740
Isop_2007
COGs: COG3379 conserved hypothetical protein; InterPro IPR002591; KEGG: hor:Hore_17270 type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
     0.685
Isop_2198
COGs: COG3379 conserved hypothetical protein; InterPro IPR005829: IPR002591; KEGG: htu:Htur_5256 type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
 
     0.675
Isop_3042
Eight transmembrane protein EpsH; InterPro IPR013426: IPR019127; KEGG: dvl:Dvul_3054 eight transmembrane protein EpsH; PFAM: Exosortase EpsH-related; SPTR: Eight transmembrane protein EpsH; TIGRFAM: eight transmembrane protein EpsH; PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: eight transmembrane protein EpsH (proposed exosortase).
 
     0.560
Isop_1658
COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterPro IPR019734: IPR013026: IPR011260: IPR001440; KEGG: psl:Psta_3991 RNA polymerase alpha subunit domain protein; PFAM: RNA polymerase alpha subunit domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SPTR: RNA polymerase alpha subunit domain protein; PFAM: Tetratricopeptide repeat; Bacterial RNA polymerase, alpha chain C terminal domain.
 
 0.556
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.544
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
   
   0.526
Isop_2985
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: sin:YN1551_2013 ankyrin; PFAM: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
   
 0.504
Isop_3043
EpsI family protein; InterPro IPR014263; KEGG: dba:Dbac_2581 EpsI family protein; SPTR: EpsI family protein; TIGRFAM: EpsI family protein; PFAM: Protein of unknown function (DUF3485); TIGRFAM: EpsI family protein.
 
     0.496
Isop_3022
Hypothetical protein; InterPro IPR000983: IPR001120: IPR012902; KEGG: rba:RB11016 signal peptide; SPTR: Putative uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; Protein of unknown function (DUF1559); TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
  
    0.485
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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