STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_3073Amidinotransferase; COGs: COG1834 N-Dimethylarginine dimethylaminohydrolase; InterPro IPR003198; KEGG: psl:Psta_3749 amidinotransferase; PFAM: amidinotransferase; SPTR: Amidinotransferase; PFAM: Amidinotransferase. (301 aa)    
Predicted Functional Partners:
Isop_1423
COGs: COG1915 conserved hypothetical protein; InterPro IPR005239: IPR007545; KEGG: psl:Psta_3748 LOR/SDH bifunctional protein conserved domain protein; PFAM: LOR/SDH bifunctional protein conserved domain protein; SPTR: LOR/SDH bifunctional protein conserved domain protein; PFAM: LOR/SDH bifunctional enzyme conserved region; TIGRFAM: conserved hypothetical protein TIGR00300.
  
  0.993
arcB
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
    
 0.913
Isop_3291
Arginine decarboxylase; COGs: COG1945 conserved hypothetical protein; InterPro IPR002724; KEGG: aca:ACP_1744 pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: Arginine decarboxylase, pyruvoyl-dependent; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent.
     
  0.900
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
    
  0.900
Isop_3072
COGs: COG2062 Phosphohistidine phosphatase SixA; InterPro IPR013078; KEGG: nde:NIDE2414 hypothetical protein; PFAM: Phosphoglycerate mutase; SPTR: Putative phosphohistidine phosphatase, SixA; PFAM: Phosphoglycerate mutase family; TIGRFAM: phosphohistidine phosphatase SixA.
 
     0.804
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049: IPR000362: IPR003031: IPR020557; KEGG: psl:Psta_0383 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; manually curated; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
     
  0.800
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.589
Isop_1251
UspA domain-containing protein; COGs: COG0531 Amino acid transporter; InterPro IPR006016; KEGG: pcu:pc0262 hypothetical protein; PFAM: UspA domain-containing protein; SPTR: Amino acid permease-associated region; PFAM: Universal stress protein family.
  
  
 0.562
Isop_0016
KEGG: eba:ebA1583 hypothetical protein; SPTR: Putative uncharacterized protein.
   
    0.421
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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