STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3087COGs: COG0515 Serine/threonine protein kinase; InterProIPR017441: IPR008271: IPR020635: IPR002290: IPR 000719: IPR017442; KEGG: psl:Psta_4397 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase; PFAM: Protein kinase domain. (423 aa)    
Predicted Functional Partners:
Isop_3004
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932: IPR014045: IPR010822; KEGG: psl:Psta_1567 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C.
 
   0.807
Isop_3386
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045: IPR001932; KEGG: plm:Plim_2397 phosphoprotein phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: Protein phosphatase; PFAM: Protein phosphatase 2C.
  
   0.806
Isop_1821
KEGG: plm:Plim_2849 tyrosine protein kinase; SPTR: Tyrosine protein kinase.
  
     0.588
Isop_1442
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR005467: IPR001789: IPR003661: IPR003594: IPR 004358; KEGG: sus:Acid_4297 response regulator receiver sensor signal transduction histidine kinase; PFAM: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Response regulator receiver sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyras [...]
 
    
 0.574
Isop_3088
phospholipase/Carboxylesterase; COGs: COG4099 peptidase; InterPro IPR003140; KEGG: rba:RB9546 putative a hydrolase; PFAM: phospholipase/Carboxylesterase; SPTR: Putative uncharacterized protein; PFAM: Dienelactone hydrolase family.
       0.405
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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