STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3125COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: adg:Adeg_0074 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (418 aa)    
Predicted Functional Partners:
Isop_0086
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014027; KEGG: nml:Namu_4191 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase; SPTR: Nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; [...]
 
 0.990
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.916
Isop_0382
UTP--glucose-1-phosphate uridylyltransferase; COGs: COG4284 UDP-glucose pyrophosphorylase; InterPro IPR002618; KEGG: rba:RB6977 UDP-N-acetylhexosamine pyrophosphorylase; PFAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP--glucose-1-phosphate uridylyltransferase subfamily; PFAM: UTP--glucose-1-phosphate uridylyltransferase.
     
  0.900
Isop_3126
ABC transporter related protein; COGs: COG1134 ABC-type polysaccharide/polyol phosphate transport system ATPase component; InterPro IPR003593: IPR003439; KEGG: cyh:Cyan8802_2759 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
  
  
 0.815
Isop_3124
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cyc:PCC7424_5786 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase group 1; PFAM: Glycosyl transferases group 1.
  
  
 0.810
Isop_0751
acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
  0.808
Isop_3621
acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
  0.808
Isop_3123
COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: afo:Afer_1817 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase family 2; PFAM: Glycosyl transferase family 2.
  
  
 0.804
Isop_1639
Glutamine--scyllo-inositol transaminase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: rca:Rcas_0781 glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: Glutamine--scyllo-inositol transaminase; SPTR: Glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.766
Isop_3093
Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: psl:Psta_4663 glycosyl transferase family 4; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Glycosyl transferase family 4; PFAM: Glycosyl transferase family 4.
  
 0.764
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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