STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_3129Capsular exopolysaccharide family; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR005702: IPR003856; KEGG: rce:RC1_4006 succinoglycan biosynthesis transport protein ExoP; PFAM: lipopolysaccharide biosynthesis protein; SPTR: Putative uncharacterized protein; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family. (812 aa)    
Predicted Functional Partners:
Isop_0221
Soluble ligand binding domain protein; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR019554; KEGG: rba:RB754 polysaccharide export protein; PFAM: Soluble ligand binding domain; SPTR: Wza; PFAM: Polysaccharide biosynthesis/export protein; SLBB domain.
 
 
 0.954
Isop_1082
Polysaccharide export protein; COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715; KEGG: rba:RB754 polysaccharide export protein; PFAM: polysaccharide export protein; SPTR: Probable polysaccharide export protein; PFAM: Polysaccharide biosynthesis/export protein.
 
 
 0.947
Isop_3192
COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: gme:Gmet_2031 sugar transferase; PFAM: sugar transferase; SPTR: Sugar transferase, PEP-CTERM system associated; PFAM: Bacterial sugar transferase.
 
  
 0.933
Isop_0923
COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: cyb:CYB_1783 sugar transferase family protein; PFAM: sugar transferase; SPTR: Bacterial sugar transferase family protein; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
 
  
 0.929
Isop_3128
KEGG: plm:Plim_3885 O-antigen polymerase; SPTR: O-antigen polymerase; PFAM: O-Antigen ligase.
  
  
 0.667
Isop_0330
Hypothetical protein; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451: IPR018357; KEGG: scl:sce6563 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Bacterial transferase hexapeptide (three repeats).
 
  
 0.651
Isop_3125
COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: adg:Adeg_0074 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
     
 0.624
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.615
Isop_2670
NAD-dependent formate dehydrogenase flavoprotein subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: mno:Mnod_8359 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F [...]
     
 0.613
Isop_3127
ABC-2 type transporter; COGs: COG1682 ABC-type polysaccharide/polyol phosphate export systems permease component; InterPro IPR000412: IPR013525; KEGG: chl:Chy400_2271 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 type transporter; PFAM: ABC-2 type transporter.
     
 0.613
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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