STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3130InterPro IPR003644; KEGG: ter:Tery_1772 Na-Ca exchanger/integrin-beta4; PFAM: Na-Ca exchanger/integrin-beta4; SMART: Na-Ca exchanger/integrin-beta4; SPTR: Na-Ca exchanger/integrin-beta4; PFAM: Calx-beta domain. (1478 aa)    
Predicted Functional Partners:
Isop_1073
Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease; InterPro IPR000209: IPR002884; KEGG: mar:MAE_12430 hypothetical protein; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; Proprotein convertase P; SPTR: Putative uncharacterized protein; PFAM: Proprotein convertase P-domain; Subtilase family.
 
 
 0.681
Isop_1806
Conserved repeat domain protein; InterPro IPR006626: IPR003644: IPR001434: IPR002884; KEGG: hau:Haur_4998 Na-Ca exchanger/integrin-beta4; PFAM: Proprotein convertase P; SMART: Na-Ca exchanger/integrin-beta4; Parallel beta-helix repeat; SPTR: Integrin alpha chain; TIGRFAM: conserved repeat domain protein; PFAM: Calx-beta domain; Proprotein convertase P-domain; TIGRFAM: conserved repeat domain.
  
 
   0.617
Isop_1805
Proprotein convertase P; COGs: COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease; InterPro IPR018247: IPR002884; KEGG: scl:sce1039 hypothetical protein; PFAM: Proprotein convertase P; SPTR: Serine protease, subtilase family protein; PFAM: Proprotein convertase P-domain.
  
 
   0.405
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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