STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3150Transcriptional repressor, CopY family; COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: mxa:MXAN_0190 hypothetical protein; PFAM: Penicillinase repressor; SPTR: Putative uncharacterized protein; PFAM: Penicillinase repressor. (196 aa)    
Predicted Functional Partners:
Isop_3151
Peptidase M56 BlaR1; InterPro IPR008756; KEGG: sus:Acid_5553 peptidase M56, BlaR1; PFAM: peptidase M56 BlaR1; SPTR: Peptidase M56, BlaR1.
 
 
 0.983
Isop_1289
Transcriptional repressor, CopY family; COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: psl:Psta_1920 transcriptional repressor, CopY family; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family; PFAM: Penicillinase repressor.
  
  
 
0.923
purE
5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.603
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
       0.603
Isop_1415
DNA mismatch repair protein MutS domain protein; COGs: COG0249 Mismatch repair ATPase (MutS family); InterPro IPR000432; KEGG: afw:Anae109_2424 DNA mismatch repair protein MutS domain-containing protein; PFAM: DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS domain protein; SPTR: DNA mismatch repair protein MutS domain protein; PFAM: MutS domain V.
  
     0.457
Isop_3147
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR003594; KEGG: sus:Acid_7798 response regulator receiver protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
     0.420
Isop_2897
KEGG: mxa:MXAN_7038 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.411
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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