Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_3164KEGG: hla:Hlac_0734 hypothetical protein; SPTR: Putative uncharacterized protein. (71 aa)    
Predicted Functional Partners:
Isop_3163
KEGG: srm:SRM_01224 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Isop_3504
Beta-carotene 15,15'-monooxygenase, Brp/Blh family; Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal. Belongs to the Brp/Blh beta-carotene diooxygenase family.
  
     0.547
Isop_3594
COGs: COG3361 conserved hypothetical protein; KEGG: scl:sce2492 hypothetical protein; SPTR: Putative uncharacterized protein yqjF; PFAM: Uncharacterized conserved protein (COG2071).
  
     0.547
Isop_3175
KEGG: mrb:Mrub_1590 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.502
Isop_2043
Hypothetical protein; InterPro IPR012902; KEGG: rba:RB6458 signal peptide; SPTR: Putative uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; Protein of unknown function (DUF1559); TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
  
     0.415
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR020558: IPR004404: IPR000581; KEGG: rxy:Rxyl_1326 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
       0.400
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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