STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3181Tex-like protein; COGs: COG2183 Transcriptional accessory protein; InterPro IPR006641: IPR003029: IPR018974: IPR018316; KEGG: plm:Plim_2413 RNA binding S1 domain protein; PFAM: Tex-like protein-like; Tubulin/FtsZ, 2-layer sandwich domain; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; SPTR: Ribosomal protein S1-like RNA-binding domain; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region. (1315 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.789
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.758
Isop_1658
COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterPro IPR019734: IPR013026: IPR011260: IPR001440; KEGG: psl:Psta_3991 RNA polymerase alpha subunit domain protein; PFAM: RNA polymerase alpha subunit domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SPTR: RNA polymerase alpha subunit domain protein; PFAM: Tetratricopeptide repeat; Bacterial RNA polymerase, alpha chain C terminal domain.
   
 0.707
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.705
nnrE
Carbohydrate kinase, YjeF related protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.
    
   0.534
Isop_1787
YjeF-family domain-containing protein; COGs: COG0062 conserved hypothetical protein; InterPro IPR004443; KEGG: rxy:Rxyl_0802 YjeF-related protein-like protein; PFAM: YjeF-family domain-containing protein; SPTR: Carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; TIGRFAM: yjeF N-terminal region.
    
   0.534
atpD
ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
 
 0.449
Isop_3600
Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR019734: IPR013026: IPR001440; KEGG: mac:MA3293 hypothetical protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Putative uncharacterized protein; PFAM: Tetratricopeptide repeat.
  
 
  0.446
Isop_2713
Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR019734: IPR013026: IPR001440; KEGG: met:M446_6666 peptidase C14 caspase catalytic subunit P20; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Peptidase C14 caspase catalytic subunit p20; PFAM: Tetratricopeptide repeat.
  
 
  0.404
Isop_3182
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: plm:Plim_3659 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: ABC transporter, permease protein; PFAM: Predicted permease.
       0.404
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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