STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_3229COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001307: IPR001763; KEGG: rmr:Rmar_0983 rhodanese domain protein; PFAM: Rhodanese domain protein; PRIAM: Thiosulfate sulfurtransferase; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Rhodanese-like domain. (288 aa)    
Predicted Functional Partners:
Isop_1999
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763: IPR001307; KEGG: pfl:PFL_0553 fused rhodanese domain-containing protein/phosphatidylserine decarboxylase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein/phosphatidylserine decarboxylase; manually curated; PFAM: Rhodanese-like domain.
  
  
 
0.925
Isop_2069
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763: IPR001307; KEGG: rxy:Rxyl_2802 thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Thiosulfate sulfurtransferase; PFAM: Rhodanese-like domain.
  
  
 
0.921
Isop_0815
Cysteine desulfurase IscS; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192: IPR016454; KEGG: cre:CHLREDRAFT_191269 cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; PFAM: Aminotransferase class-V.
   
 0.912
cysH
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
    
 0.912
Isop_1056
COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117: IPR006067: IPR006066; KEGG: psl:Psta_1330 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Sulfite reductase (NADPH); SPTR: Sulfite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase.
    
 0.912
Isop_2132
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: rmr:Rmar_1215 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
   
 0.912
Isop_1634
COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557: IPR018177: IPR001236; KEGG: psl:Psta_3289 lactate/malate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: L-lactate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; Belongs to the LDH/MDH superfamily.
   
 
  0.903
Isop_0587
L-aspartate aminotransferase apoenzyme; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR004838: IPR001176; KEGG: plm:Plim_0135 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
     
  0.900
Isop_3230
COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: rmr:Rmar_0984 Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated SufE; SPTR: Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated domain.
 
     0.849
Isop_2293
COGs: COG0031 Cysteine synthase; InterPro IPR005856: IPR005859: IPR001926; KEGG: psl:Psta_1771 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases.
  
 
 0.833
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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