| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Isop_3175 | Isop_3253 | Isop_3175 | Isop_3253 | KEGG: mrb:Mrub_1590 hypothetical protein; SPTR: Putative uncharacterized protein. | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | 0.471 |
| Isop_3252 | Isop_3253 | Isop_3252 | Isop_3253 | Hypothetical protein; KEGG: shl:Shal_1981 histidine kinase; SPTR: Histidine kinase. | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | 0.773 |
| Isop_3252 | Isop_3254 | Isop_3252 | Isop_3254 | Hypothetical protein; KEGG: shl:Shal_1981 histidine kinase; SPTR: Histidine kinase. | Hypothetical protein; InterPro IPR022272; KEGG: tro:trd_1637 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.539 |
| Isop_3253 | Isop_3175 | Isop_3253 | Isop_3175 | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | KEGG: mrb:Mrub_1590 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.471 |
| Isop_3253 | Isop_3252 | Isop_3253 | Isop_3252 | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | Hypothetical protein; KEGG: shl:Shal_1981 histidine kinase; SPTR: Histidine kinase. | 0.773 |
| Isop_3253 | Isop_3254 | Isop_3253 | Isop_3254 | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | Hypothetical protein; InterPro IPR022272; KEGG: tro:trd_1637 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.539 |
| Isop_3253 | Isop_3505 | Isop_3253 | Isop_3505 | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | Rhodopsin; COGs: COG5524 Bacteriorhodopsin; InterPro IPR017402: IPR001425: IPR018229; KEGG: srm:SRM_01698 Xanthorhodopsin; PFAM: rhodopsin; SPTR: Xanthorhodopsin; PFAM: Bacteriorhodopsin-like protein. | 0.520 |
| Isop_3253 | pdxH | Isop_3253 | Isop_0296 | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.900 |
| Isop_3253 | pdxJ | Isop_3253 | Isop_2767 | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.912 |
| Isop_3253 | ribA | Isop_3253 | Isop_1891 | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.415 |
| Isop_3254 | Isop_3252 | Isop_3254 | Isop_3252 | Hypothetical protein; InterPro IPR022272; KEGG: tro:trd_1637 hypothetical protein; SPTR: Putative uncharacterized protein. | Hypothetical protein; KEGG: shl:Shal_1981 histidine kinase; SPTR: Histidine kinase. | 0.539 |
| Isop_3254 | Isop_3253 | Isop_3254 | Isop_3253 | Hypothetical protein; InterPro IPR022272; KEGG: tro:trd_1637 hypothetical protein; SPTR: Putative uncharacterized protein. | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | 0.539 |
| Isop_3505 | Isop_3253 | Isop_3505 | Isop_3253 | Rhodopsin; COGs: COG5524 Bacteriorhodopsin; InterPro IPR017402: IPR001425: IPR018229; KEGG: srm:SRM_01698 Xanthorhodopsin; PFAM: rhodopsin; SPTR: Xanthorhodopsin; PFAM: Bacteriorhodopsin-like protein. | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | 0.520 |
| pdxH | Isop_3253 | Isop_0296 | Isop_3253 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | 0.900 |
| pdxH | pdxJ | Isop_0296 | Isop_2767 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.912 |
| pdxH | ribA | Isop_0296 | Isop_1891 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.415 |
| pdxJ | Isop_3253 | Isop_2767 | Isop_3253 | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | 0.912 |
| pdxJ | pdxH | Isop_2767 | Isop_0296 | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.912 |
| pdxJ | ribA | Isop_2767 | Isop_1891 | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.554 |
| ribA | Isop_3253 | Isop_1891 | Isop_3253 | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | InterPro IPR011576; KEGG: srm:SRM_01614 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase. | 0.415 |