STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
Isop_3271COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003661: IPR 003594: IPR001789: IPR005467: IPR000700: IPR008207: IPR013767; KEGG: psl:Psta_1412 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid h [...] (973 aa)    
Predicted Functional Partners:
Isop_3147
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR003594; KEGG: sus:Acid_7798 response regulator receiver protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.983
Isop_3686
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789; KEGG: lch:Lcho_3971 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.973
Isop_2636
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR010822: IPR003594: IPR001932; KEGG: cli:Clim_1832 putative PAS/PAC sensor protein; PFAM: Stage II sporulation protein E; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Putative PAS/PAC sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Stage II sporulation protein E (SpoIIE).
 
  
 0.968
Isop_3677
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: ter:Tery_3248 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.967
Isop_1972
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013767: IPR003661: IPR003594: IPR 001789: IPR008207: IPR000014: IPR004358: IPR000896: IPR005467; KEGG: rba:RB159 sensory transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine k [...]
 
 
0.964
Isop_1153
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: dsa:Desal_1726 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Hpt sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
0.961
Isop_1842
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: afw:Anae109_0804 multi-sensor signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.958
Isop_1453
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: psl:Psta_3399 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.956
Isop_0022
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: psl:Psta_2596 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Phosphate regulon response regulator PhoB; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.954
Isop_1841
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207: IPR004105: IPR003594: IPR002545: IPR 001789: IPR004358: IPR005467; KEGG: aeh:Mlg_0359 CheA signal transduction histidine kinases; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SPTR: CheA signal transduction histidine kin [...]
 
 
 0.952
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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