STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3345InterPro IPR004155; KEGG: rrs:RoseRS_1736 heat repeat-containing PBS lyase; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: PBS lyase HEAT domain protein repeat-containing protein. (342 aa)    
Predicted Functional Partners:
Isop_0503
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: svi:Svir_35400 NAD-dependent protein deacetylase, SIR2 family; PFAM: Silent information regulator protein Sir2; SPTR: NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family.
   
   0.772
Isop_1139
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: scl:sce7444 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: Transcriptional regulatory protein, Sir2 family; manually curated; PFAM: Sir2 family.
   
   0.772
Isop_2363
Protein of unknown function DUF820; InterPro IPR008538; KEGG: mar:MAE_05220 hypothetical protein; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.620
Isop_2365
Protein of unknown function DUF820; InterPro IPR008538; KEGG: mar:MAE_05220 hypothetical protein; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.610
Isop_3032
KEGG: npu:Npun_R2871 hypothetical protein; SPTR: Phosphoribosylaminoimidazole synthetase.
  
     0.600
Isop_2364
InterPro IPR008538; KEGG: cyh:Cyan8802_0022 protein of unknown function DUF820; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.588
Isop_0494
Protein of unknown function DUF820; InterPro IPR008538; KEGG: rca:Rcas_2194 hypothetical protein; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.538
Isop_3082
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680: IPR019782: IPR017986: IPR019781; KEGG: hoh:Hoch_3099 serine/threonine protein kinase with WD40 repeats; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase with WD40 repeats; PFAM: WD domain, G-beta repeat.
 
    0.537
Isop_2392
Protein of unknown function DUF790; COGs: COG3372 conserved hypothetical protein; InterPro IPR008508; KEGG: scl:sce6812 hypothetical protein; PFAM: protein of unknown function DUF790; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF790).
  
     0.487
Isop_3344
ABC transporter related protein; COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterPro IPR003439: IPR017871: IPR003593; KEGG: hoh:Hoch_5204 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
  
    0.481
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.