STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_3365KEGG: pth:PTH_0156 hypothetical protein; SPTR: Hypothetical membrane protein. (399 aa)    
Predicted Functional Partners:
Isop_3363
COGs: COG0433 ATPase; InterPro IPR003593; KEGG: sat:SYN_01844 putative cytoplasmic protein; SMART: AAA ATPase; SPTR: Hypothetical cytosolic protein; PFAM: Domain of unknown function DUF87.
 
     0.930
Isop_3376
Type III restriction protein res subunit; InterPro IPR006935: IPR014001; KEGG: aeh:Mlg_1542 DEAD/DEAH box helicase domain-containing protein; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: DEAD/DEAH box helicase domain protein; PFAM: Type III restriction enzyme, res subunit.
  
 
 0.757
Isop_3364
NurA domain protein; InterPro IPR018977; KEGG: sat:SYN_01845 putative cytoplasmic protein; PFAM: NurA domain; SPTR: Hypothetical cytosolic protein; PFAM: NurA domain.
       0.714
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.575
Isop_3368
COGs: COG1715 Restriction endonuclease; InterPro IPR007560; KEGG: bts:Btus_1743 restriction endonuclease; PFAM: restriction endonuclease; SPTR: Restriction endonuclease; PFAM: Restriction endonuclease.
  
  
 0.551
Isop_3366
KEGG: scl:sce1944 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.550
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.497
Isop_1361
KEGG: syn:slr1959 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.477
Isop_1498
KEGG: scl:sce5406 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: KAP family P-loop domain.
  
  
 0.477
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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