Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_3460Hypothetical protein; KEGG: mmu:77215 keratin associated protein 5-3; SPTR: Putative uncharacterized protein ENSMUSP00000081452. (226 aa)    
Predicted Functional Partners:
Isop_2584
Hypothetical protein; KEGG: hwa:HQ1193A cell surface glycoprotein; SPTR: Probable cell surface glycoprotein.
  
     0.609
Isop_3495
Hypothetical protein; KEGG: mtp:Mthe_1626 periplasmic copper-binding; SPTR: Putative lipoprotein.
  
     0.548
Isop_1461
Hypothetical protein; KEGG: mca:MCA2974 PKD domain-containing protein; SPTR: PKD domain protein.
  
     0.537
Isop_0706
Protein of unknown function DUF1565; InterPro IPR011506: IPR000209: IPR011459: IPR006626; KEGG: mar:MAE_50880 hypothetical protein; PFAM: protein of unknown function DUF1565; Planctomycete extracellular domain protein; peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Peptidase families S8 and S53 domain protein; PFAM: Protein of unknown function (DUF1565); Subtilase family.
  
     0.519
Isop_2736
KEGG: mxa:MXAN_5625 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.517
Isop_1856
Glyoxalase/bleomycin resistance protein/dioxygenase; InterPro IPR004360; KEGG: cja:CJA_0178 glyoxylase family protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxylase family protein; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
  
     0.514
Isop_2175
ADP-ribosylation/Crystallin J1; COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: syf:Synpcc7942_1562 ADP-ribosylglycohydrolase-like; PFAM: ADP-ribosylation/Crystallin J1; SPTR: Probable ADP-ribosylglycohydrolase; PFAM: ADP-ribosylglycohydrolase.
  
     0.508
Isop_2510
Peptidase M10A and M12B matrixin and adamalysin; InterPro IPR001818: IPR021190: IPR006026; KEGG: nml:Namu_5076 serine/threonine protein kinase; PFAM: peptidase M10A and M12B matrixin and adamalysin; SMART: peptidase metallopeptidase; SPTR: Serine/threonine protein kinase; PFAM: Matrixin; TIGRFAM: conserved repeat domain.
  
     0.508
Isop_3041
Hypothetical protein; KEGG: dan:Dana_GF24314 GF24314 gene product from transcript GF24314-RA; SPTR: Minus agglutinin.
  
     0.506
Isop_3545
Pyrrolo-quinoline quinone repeat-containing protein; InterPro IPR002372: IPR019734: IPR018391; KEGG: psl:Psta_2917 hypothetical protein; PFAM: Pyrrolo-quinoline quinone repeat-containing protein; SPTR: Putative uncharacterized protein.
  
     0.496
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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