STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_34941-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: psl:Psta_3844 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: AIR carboxylase. (272 aa)    
Predicted Functional Partners:
Isop_1940
Asparagine synthase; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR001962: IPR005232; KEGG: psl:Psta_4402 ExsB family protein; PFAM: asparagine synthase; SPTR: ExsB family protein; manually curated; PFAM: Asparagine synthase; TIGRFAM: conserved hypothetical protein TIGR00268.
 
  
 0.933
Isop_2077
Protein of unknown function DUF111; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: plm:Plim_2400 protein of unknown function DUF111; PFAM: protein of unknown function DUF111; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF111; TIGRFAM: conserved hypothetical protein TIGR00299; Belongs to the LarC family.
 
  
 0.916
Isop_3476
Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: sno:Snov_3500 protein of unknown function DUF2088; PFAM: Protein of unknown function DUF2088; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088).
 
  
 0.883
Isop_0004
Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: dol:Dole_2523 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088).
 
  
 0.872
Isop_1424
Cobalamin (vitamin B12) biosynthesis CbiM protein; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: rrs:RoseRS_0174 cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM.
 
    0.703
nnrD
Carbohydrate kinase, YjeF related protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
     
 0.693
Isop_1425
ABC transporter related protein; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439: IPR003339: IPR017871: IPR003593; KEGG: tbi:Tbis_0515 cobalt ABC transporter ATPase subunit; PFAM: ABC transporter related; cobalt transport protein; SMART: AAA ATPase; SPTR: Cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter; Cobalt transport protein.
  
    0.558
Isop_3402
COGs: COG2006 conserved hypothetical protein; InterPro IPR006311: IPR017909; KEGG: dma:DMR_13230 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF362); TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
     0.455
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.