| node1 | node2 | node1 annotation | node2 annotation | score |
| Isop_0989 | Isop_1566 | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR019845: IPR002060; KEGG: mxa:MXAN_0896 phytoene synthetase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase; PFAM: Squalene/phytoene synthase. | 0.555 |
| Isop_0989 | Isop_2284 | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH. | 0.589 |
| Isop_0989 | Isop_2285 | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | 0.536 |
| Isop_0989 | Isop_3497 | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | Squalene-associated FAD-dependent desaturase; COGs: COG3349 conserved hypothetical protein; InterPro IPR017830: IPR002937: IPR001613; KEGG: plm:Plim_3204 squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; SPTR: Carotene 7,8-desaturase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: squalene-associated FAD-dependent desaturase. | 0.435 |
| Isop_0989 | Isop_3498 | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR002060: IPR019845; KEGG: sus:Acid_1266 farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase. | 0.562 |
| Isop_0989 | Isop_3499 | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | Squalene synthase HpnC; COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR017827: IPR002060; KEGG: plm:Plim_2245 squalene synthase HpnC; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase-related protein; TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; TIGRFAM: squalene synthase HpnC. | 0.473 |
| Isop_1566 | Isop_0989 | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR019845: IPR002060; KEGG: mxa:MXAN_0896 phytoene synthetase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase; PFAM: Squalene/phytoene synthase. | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | 0.555 |
| Isop_1566 | Isop_2285 | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR019845: IPR002060; KEGG: mxa:MXAN_0896 phytoene synthetase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase; PFAM: Squalene/phytoene synthase. | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | 0.426 |
| Isop_1566 | Isop_3497 | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR019845: IPR002060; KEGG: mxa:MXAN_0896 phytoene synthetase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase; PFAM: Squalene/phytoene synthase. | Squalene-associated FAD-dependent desaturase; COGs: COG3349 conserved hypothetical protein; InterPro IPR017830: IPR002937: IPR001613; KEGG: plm:Plim_3204 squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; SPTR: Carotene 7,8-desaturase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: squalene-associated FAD-dependent desaturase. | 0.781 |
| Isop_1566 | Isop_3498 | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR019845: IPR002060; KEGG: mxa:MXAN_0896 phytoene synthetase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase; PFAM: Squalene/phytoene synthase. | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR002060: IPR019845; KEGG: sus:Acid_1266 farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase. | 0.924 |
| Isop_2284 | Isop_0989 | Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH. | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | 0.589 |
| Isop_2284 | Isop_2285 | Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH. | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | 0.905 |
| Isop_2284 | Isop_3497 | Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH. | Squalene-associated FAD-dependent desaturase; COGs: COG3349 conserved hypothetical protein; InterPro IPR017830: IPR002937: IPR001613; KEGG: plm:Plim_3204 squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; SPTR: Carotene 7,8-desaturase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: squalene-associated FAD-dependent desaturase. | 0.607 |
| Isop_2285 | Isop_0989 | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | 0.536 |
| Isop_2285 | Isop_1566 | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR019845: IPR002060; KEGG: mxa:MXAN_0896 phytoene synthetase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase; PFAM: Squalene/phytoene synthase. | 0.426 |
| Isop_2285 | Isop_2284 | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH. | 0.905 |
| Isop_2285 | Isop_3497 | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | Squalene-associated FAD-dependent desaturase; COGs: COG3349 conserved hypothetical protein; InterPro IPR017830: IPR002937: IPR001613; KEGG: plm:Plim_3204 squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; SPTR: Carotene 7,8-desaturase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: squalene-associated FAD-dependent desaturase. | 0.701 |
| Isop_2285 | Isop_3498 | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR002060: IPR019845; KEGG: sus:Acid_1266 farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase. | 0.487 |
| Isop_2285 | Isop_3499 | COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. | Squalene synthase HpnC; COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR017827: IPR002060; KEGG: plm:Plim_2245 squalene synthase HpnC; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase-related protein; TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; TIGRFAM: squalene synthase HpnC. | 0.518 |
| Isop_3497 | Isop_0989 | Squalene-associated FAD-dependent desaturase; COGs: COG3349 conserved hypothetical protein; InterPro IPR017830: IPR002937: IPR001613; KEGG: plm:Plim_3204 squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; SPTR: Carotene 7,8-desaturase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: squalene-associated FAD-dependent desaturase. | COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2. | 0.435 |