STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_3499Squalene synthase HpnC; COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR017827: IPR002060; KEGG: plm:Plim_2245 squalene synthase HpnC; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase-related protein; TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; TIGRFAM: squalene synthase HpnC. (333 aa)    
Predicted Functional Partners:
Isop_3497
Squalene-associated FAD-dependent desaturase; COGs: COG3349 conserved hypothetical protein; InterPro IPR017830: IPR002937: IPR001613; KEGG: plm:Plim_3204 squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; SPTR: Carotene 7,8-desaturase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: squalene-associated FAD-dependent desaturase.
 
   
 0.930
Isop_3498
COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR002060: IPR019845; KEGG: sus:Acid_1266 farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase.
 
    
0.847
Isop_0988
COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR014105: IPR006076; KEGG: rca:Rcas_2535 zeta-phytoene desaturase; PFAM: FAD dependent oxidoreductase; SPTR: Zeta-phytoene desaturase; TIGRFAM: phytoene desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: phytoene desaturase.
 
  
 0.775
Isop_1567
COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR008150: IPR014105: IPR002937; KEGG: hau:Haur_3185 zeta-phytoene desaturase; PFAM: amine oxidase; SPTR: Zeta-phytoene desaturase; TIGRFAM: phytoene desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: phytoene desaturase.
 
  
 0.764
Isop_3519
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR006424: IPR020831: IPR020828: IPR020829: IPR 020832: IPR020830; KEGG: plm:Plim_0647 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Strongly similar to glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phospha [...]
   
  
 0.645
Isop_0881
MATE efflux family protein; COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: aca:ACP_0275 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family.
   
  
 0.617
Isop_0995
InterPro IPR002123; KEGG: bse:Bsel_2210 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase; PFAM: Acyltransferase.
 
  
 0.533
Isop_2801
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR013027; KEGG: hau:Haur_1711 FAD dependent oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase.
 
  
 0.533
Isop_2285
COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase.
 
  
 0.518
Isop_1801
FAD dependent oxidoreductase; COGs: COG1233 Phytoene dehydrogenase and related protein; InterPro IPR006076; KEGG: afw:Anae109_3492 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; manually curated; PFAM: Flavin containing amine oxidoreductase.
 
  
 0.507
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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