STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_3634Thioesterase superfamily protein; COGs: COG0824 thioesterase; InterPro IPR006684: IPR006683; KEGG: plm:Plim_2936 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: Putative uncharacterized protein; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family. (144 aa)    
Predicted Functional Partners:
Isop_2003
KR domain protein; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014031: IPR014043: IPR006163: IPR013968: IPR 009081; KEGG: glo:Glov_2267 polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; phosphopantetheine-binding; SPTR: Polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: acyl carrier protein.
  
 
 0.838
Isop_2004
COGs: COG3321 Polyketide synthase modules and related protein; InterPro IPR014030: IPR014031: IPR013114; KEGG: glo:Glov_2268 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: Beta-ketoacyl synthase; PFAM: FabA-like domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: PfaB family protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
  
 0.672
Isop_1367
RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
   0.559
Isop_2321
InterPro IPR000090; KEGG: aeh:Mlg_0710 flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein fliG; PFAM: FliG C-terminal domain.
    
   0.559
Isop_2002
COGs: COG3321 Polyketide synthase modules and related protein; InterPro IPR014030: IPR018201; KEGG: gur:Gura_2012 erythronolide synthase; PFAM: Beta-ketoacyl synthase; SPTR: Erythronolide synthase; PFAM: Beta-ketoacyl synthase, N-terminal domain.
   
  
 0.530
Isop_0450
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043: IPR004410; KEGG: psl:Psta_1725 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
  
  
 0.508
Isop_3635
KEGG: cre:CHLREDRAFT_195506 protein with ARF GTPase-activating domain; SPTR: Protein with ARF GTPase-activating domain.
       0.447
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.