Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_3678InterPro IPR010496; KEGG: dfe:Dfer_0069 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080). (253 aa)    
Predicted Functional Partners:
Isop_3679
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: ava:Ava_4240 twin-arginine translocation pathway signal; PFAM: sulfatase; SPTR: Twin-arginine translocation pathway signal; PFAM: Sulfatase.
  
    0.777
Isop_0757
InterPro IPR010496; KEGG: caa:Caka_0473 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.765
Isop_0462
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR006311; KEGG: plm:Plim_1207 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.753
Isop_2477
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_0037 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
     0.743
Isop_3665
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: dfe:Dfer_4144 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable NADH-dependent dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.741
Isop_2174
InterPro IPR010496; KEGG: psl:Psta_3759 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative large multi-functional protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.738
Isop_1264
Hypothetical protein; KEGG: sus:Acid_2874 transmembrane prediction; SPTR: Putative uncharacterized protein.
  
     0.733
Isop_0606
InterPro IPR010496; KEGG: tra:Trad_1254 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.726
Isop_1252
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR006311: IPR000683; KEGG: plm:Plim_0111 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.724
Isop_2678
Heme-binding protein; InterPro IPR009056: IPR013427; KEGG: plm:Plim_2734 membrane-bound dehydrogenase domain protein; SPTR: Heme-binding protein; TIGRFAM: heme-binding protein; PFAM: Cytochrome c; TIGRFAM: putative heme-binding domain, Pirellula/Verrucomicrobium type.
  
     0.714
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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