Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_3679Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: ava:Ava_4240 twin-arginine translocation pathway signal; PFAM: sulfatase; SPTR: Twin-arginine translocation pathway signal; PFAM: Sulfatase. (481 aa)    
Predicted Functional Partners:
Isop_3678
InterPro IPR010496; KEGG: dfe:Dfer_0069 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
    0.777
Isop_3638
Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: sli:Slin_1433 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme.
  
 
   0.714
Isop_3680
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: chl:Chy400_1467 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase.
 
    
0.550
Isop_1845
Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: psl:Psta_4609 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme.
  
 
   0.440
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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