STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (210 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
 0.998
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.983
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.979
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.975
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
  
 
 0.950
carA
Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
  
  
 0.937
EFI16864.1
Dihydroorotate dehydrogenase, electron transfer subunit.
 
 
 0.928
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.879
EFI16263.1
Phosphoribulokinase family protein.
  
 0.798
EFI16949.1
Oxidoreductase, NAD-binding.
  
 
 0.784
Your Current Organism:
Bacteroidetes F0058
NCBI taxonomy Id: 575590
Other names: B. oral taxon 274 str. F0058, Bacteroidetes oral taxon 274 str. F0058, Bacteroidetes oral taxon 274 strain F0058
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.