STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)    
Predicted Functional Partners:
EFI17680.1
D-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.937
EFI16687.1
4-phosphoerythronate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
  
 0.922
EFI17294.1
4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
     
 0.795
EFI15863.1
Conserved hypothetical protein.
  
 
 0.749
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
      0.746
EFI16068.1
ABC transporter, ATP-binding protein.
   
   0.736
EFI16872.1
L-serine dehydratase, iron-sulfur-dependent, single chain form.
  
 
 0.679
EFI17129.1
Cysteine synthase.
  
 
 0.664
EFI16069.1
5-nucleotidase/2,3-cyclic phosphodiesterase.
       0.621
EFI16533.1
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.593
Your Current Organism:
Bacteroidetes F0058
NCBI taxonomy Id: 575590
Other names: B. oral taxon 274 str. F0058, Bacteroidetes oral taxon 274 str. F0058, Bacteroidetes oral taxon 274 strain F0058
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.