node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGG89723.1 | EGG91593.1 | HMPREF0491_00853 | HMPREF0491_00259 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; Belongs to the CinA family. | 0.995 |
EGG89723.1 | EGG91624.1 | HMPREF0491_00853 | HMPREF0491_00290 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein. | 0.942 |
EGG89723.1 | EGG91821.1 | HMPREF0491_00853 | HMPREF0491_01948 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein. | 0.912 |
EGG89723.1 | EGG91930.1 | HMPREF0491_00853 | HMPREF0491_01856 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Chorismate mutase. | 0.942 |
EGG89723.1 | EGG92286.1 | HMPREF0491_00853 | HMPREF0491_01622 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein. | 0.891 |
EGG89723.1 | birA | HMPREF0491_00853 | HMPREF0491_01392 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.944 |
EGG89723.1 | guaA | HMPREF0491_00853 | HMPREF0491_01718 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.977 |
EGG89723.1 | guaB | HMPREF0491_00853 | HMPREF0491_01882 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.866 |
EGG89723.1 | nadD | HMPREF0491_00853 | HMPREF0491_00575 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.988 |
EGG89723.1 | nadE | HMPREF0491_00853 | HMPREF0491_00890 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.998 |
EGG91593.1 | EGG89723.1 | HMPREF0491_00259 | HMPREF0491_00853 | Hypothetical protein; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.995 |
EGG91593.1 | EGG91821.1 | HMPREF0491_00259 | HMPREF0491_01948 | Hypothetical protein; Belongs to the CinA family. | Hypothetical protein. | 0.934 |
EGG91593.1 | EGG92286.1 | HMPREF0491_00259 | HMPREF0491_01622 | Hypothetical protein; Belongs to the CinA family. | Hypothetical protein. | 0.768 |
EGG91593.1 | birA | HMPREF0491_00259 | HMPREF0491_01392 | Hypothetical protein; Belongs to the CinA family. | Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.985 |
EGG91593.1 | guaA | HMPREF0491_00259 | HMPREF0491_01718 | Hypothetical protein; Belongs to the CinA family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.984 |
EGG91593.1 | guaB | HMPREF0491_00259 | HMPREF0491_01882 | Hypothetical protein; Belongs to the CinA family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.998 |
EGG91593.1 | nadD | HMPREF0491_00259 | HMPREF0491_00575 | Hypothetical protein; Belongs to the CinA family. | Nicotinate nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.996 |
EGG91593.1 | nadE | HMPREF0491_00259 | HMPREF0491_00890 | Hypothetical protein; Belongs to the CinA family. | Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.999 |
EGG91624.1 | EGG89723.1 | HMPREF0491_00290 | HMPREF0491_00853 | Hypothetical protein. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.942 |
EGG91624.1 | EGG91821.1 | HMPREF0491_00290 | HMPREF0491_01948 | Hypothetical protein. | Hypothetical protein. | 0.942 |