STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated protein cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (330 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated protein cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
EGG91969.1
CRISPR-associated protein cas4.
 
 
 
 0.998
EGG91968.1
Hypothetical protein.
 
  
 0.996
cas2-2
CRISPR-associated protein cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.995
EGG91965.1
Devr family CRISPR-associated regulatory protein.
 
   
 0.990
EGG91966.1
Hypothetical protein.
 
   
 0.990
EGG91963.1
CRISPR-associated protein cas6.
 
   
 0.989
EGG91037.1
Csm1 family CRISPR-associated protein.
 
  
 0.946
EGG91035.1
Csm3 family CRISPR-associated ramp protein.
 
     0.929
EGG91964.1
CRISPR-associated protein csx8.
       0.928
Your Current Organism:
Lachnospiraceae F0167
NCBI taxonomy Id: 575593
Other names: L. oral taxon 107 str. F0167, Lachnospiraceae oral taxon 107 str. F0167, Lachnospiraceae oral taxon 107 strain F0167
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.