| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEU30646.1 | EEU30793.1 | HMPREF0501_00051 | HMPREF0501_00198 | DNA internalization competence protein ComEC/Rec2-like protein. | ATP-dependent DNA helicase, RecQ family. | 0.472 |
| EEU30646.1 | recJ | HMPREF0501_00051 | HMPREF0501_00072 | DNA internalization competence protein ComEC/Rec2-like protein. | single-stranded-DNA-specific exonuclease RecJ. | 0.816 |
| EEU30646.1 | recQ | HMPREF0501_00051 | HMPREF0501_01565 | DNA internalization competence protein ComEC/Rec2-like protein. | ATP-dependent DNA helicase RecQ. | 0.472 |
| EEU30646.1 | ruvB | HMPREF0501_00051 | HMPREF0501_01007 | DNA internalization competence protein ComEC/Rec2-like protein. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.699 |
| EEU30646.1 | uvrC | HMPREF0501_00051 | HMPREF0501_00068 | DNA internalization competence protein ComEC/Rec2-like protein. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.623 |
| EEU30646.1 | xseA | HMPREF0501_00051 | HMPREF0501_00427 | DNA internalization competence protein ComEC/Rec2-like protein. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.400 |
| EEU30793.1 | EEU30646.1 | HMPREF0501_00198 | HMPREF0501_00051 | ATP-dependent DNA helicase, RecQ family. | DNA internalization competence protein ComEC/Rec2-like protein. | 0.472 |
| EEU30793.1 | dnaG | HMPREF0501_00198 | HMPREF0501_00174 | ATP-dependent DNA helicase, RecQ family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.448 |
| EEU30793.1 | polA | HMPREF0501_00198 | HMPREF0501_00559 | ATP-dependent DNA helicase, RecQ family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.948 |
| EEU30793.1 | recJ | HMPREF0501_00198 | HMPREF0501_00072 | ATP-dependent DNA helicase, RecQ family. | single-stranded-DNA-specific exonuclease RecJ. | 0.957 |
| EEU30793.1 | topA | HMPREF0501_00198 | HMPREF0501_00217 | ATP-dependent DNA helicase, RecQ family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
| apt | recJ | HMPREF0501_00073 | HMPREF0501_00072 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | single-stranded-DNA-specific exonuclease RecJ. | 0.835 |
| dnaG | EEU30793.1 | HMPREF0501_00174 | HMPREF0501_00198 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | ATP-dependent DNA helicase, RecQ family. | 0.448 |
| dnaG | polA | HMPREF0501_00174 | HMPREF0501_00559 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.978 |
| dnaG | recJ | HMPREF0501_00174 | HMPREF0501_00072 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | single-stranded-DNA-specific exonuclease RecJ. | 0.823 |
| dnaG | recQ | HMPREF0501_00174 | HMPREF0501_01565 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | ATP-dependent DNA helicase RecQ. | 0.448 |
| dnaG | ruvB | HMPREF0501_00174 | HMPREF0501_01007 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.420 |
| dnaG | topA | HMPREF0501_00174 | HMPREF0501_00217 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.782 |
| polA | EEU30793.1 | HMPREF0501_00559 | HMPREF0501_00198 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | ATP-dependent DNA helicase, RecQ family. | 0.948 |
| polA | dnaG | HMPREF0501_00559 | HMPREF0501_00174 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.978 |