STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEU30277.1Hypothetical protein. (272 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.843
EEU30278.1
Amidohydrolase family protein.
       0.773
EEU29560.1
Hypothetical protein.
  
     0.758
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.695
EEU29808.1
LPXTG-motif cell wall anchor domain protein.
  
    0.695
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
   0.694
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.694
EEU29841.1
KxYKxGKxW signal domain protein.
 
    0.689
EEU30279.1
Cytochrome b5-like Heme/Steroid binding domain protein.
       0.545
EEU29840.1
LytTr DNA-binding domain protein.
  
     0.512
Your Current Organism:
Lactobacillus coleohominis
NCBI taxonomy Id: 575594
Other names: L. coleohominis 101-4-CHN, Lactobacillus coleohominis 101-4-CHN
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.