| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEU29610.1 | EEU29782.1 | HMPREF0501_01617 | HMPREF0501_01247 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Ham1 family protein. | 0.953 |
| EEU29610.1 | apt | HMPREF0501_01617 | HMPREF0501_00073 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.431 |
| EEU29610.1 | gmk | HMPREF0501_01617 | HMPREF0501_00421 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.565 |
| EEU29610.1 | guaA | HMPREF0501_01617 | HMPREF0501_01335 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| EEU29610.1 | guaC | HMPREF0501_01617 | HMPREF0501_01562 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.946 |
| EEU29610.1 | hpt | HMPREF0501_01617 | HMPREF0501_01428 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.943 |
| EEU29610.1 | tilS | HMPREF0501_01617 | HMPREF0501_01427 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | 0.428 |
| EEU29610.1 | xpt | HMPREF0501_01617 | HMPREF0501_00841 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.940 |
| EEU29782.1 | EEU29610.1 | HMPREF0501_01247 | HMPREF0501_01617 | Ham1 family protein. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.953 |
| EEU29782.1 | EEU30345.1 | HMPREF0501_01247 | HMPREF0501_00723 | Ham1 family protein. | Guanylate kinase. | 0.532 |
| EEU29782.1 | EEU30829.1 | HMPREF0501_01247 | HMPREF0501_00234 | Ham1 family protein. | Phosphoribosyl transferase domain protein. | 0.452 |
| EEU29782.1 | apt | HMPREF0501_01247 | HMPREF0501_00073 | Ham1 family protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.452 |
| EEU29782.1 | gmk | HMPREF0501_01247 | HMPREF0501_00421 | Ham1 family protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.532 |
| EEU29782.1 | guaA | HMPREF0501_01247 | HMPREF0501_01335 | Ham1 family protein. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.972 |
| EEU29782.1 | guaC | HMPREF0501_01247 | HMPREF0501_01562 | Ham1 family protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.589 |
| EEU29782.1 | hpt | HMPREF0501_01247 | HMPREF0501_01428 | Ham1 family protein. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.935 |
| EEU29782.1 | tilS | HMPREF0501_01247 | HMPREF0501_01427 | Ham1 family protein. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | 0.852 |
| EEU29782.1 | xpt | HMPREF0501_01247 | HMPREF0501_00841 | Ham1 family protein. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.945 |
| EEU30345.1 | EEU29782.1 | HMPREF0501_00723 | HMPREF0501_01247 | Guanylate kinase. | Ham1 family protein. | 0.532 |
| EEU30345.1 | EEU30829.1 | HMPREF0501_00723 | HMPREF0501_00234 | Guanylate kinase. | Phosphoribosyl transferase domain protein. | 0.956 |