| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEU29743.1 | dacA | HMPREF0501_01537 | HMPREF0501_01094 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.415 |
| EEU30088.1 | EEU30090.1 | HMPREF0501_01093 | HMPREF0501_01095 | YbbR-like protein. | Hypothetical protein. | 0.625 |
| EEU30088.1 | dacA | HMPREF0501_01093 | HMPREF0501_01094 | YbbR-like protein. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.948 |
| EEU30088.1 | glmM | HMPREF0501_01093 | HMPREF0501_01092 | YbbR-like protein. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.823 |
| EEU30088.1 | glmS | HMPREF0501_01093 | HMPREF0501_01091 | YbbR-like protein. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.512 |
| EEU30090.1 | EEU30088.1 | HMPREF0501_01095 | HMPREF0501_01093 | Hypothetical protein. | YbbR-like protein. | 0.625 |
| EEU30090.1 | dacA | HMPREF0501_01095 | HMPREF0501_01094 | Hypothetical protein. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.626 |
| EEU30090.1 | glmM | HMPREF0501_01095 | HMPREF0501_01092 | Hypothetical protein. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.588 |
| argR | dacA | HMPREF0501_00423 | HMPREF0501_01094 | Arginine repressor, C-terminal domain protein; Regulates arginine biosynthesis genes. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.412 |
| argR-2 | dacA | HMPREF0501_01492 | HMPREF0501_01094 | Arginine repressor, C-terminal domain protein; Regulates arginine biosynthesis genes. | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.412 |
| dacA | EEU29743.1 | HMPREF0501_01094 | HMPREF0501_01537 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.415 |
| dacA | EEU30088.1 | HMPREF0501_01094 | HMPREF0501_01093 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | YbbR-like protein. | 0.948 |
| dacA | EEU30090.1 | HMPREF0501_01094 | HMPREF0501_01095 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Hypothetical protein. | 0.626 |
| dacA | argR | HMPREF0501_01094 | HMPREF0501_00423 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Arginine repressor, C-terminal domain protein; Regulates arginine biosynthesis genes. | 0.412 |
| dacA | argR-2 | HMPREF0501_01094 | HMPREF0501_01492 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Arginine repressor, C-terminal domain protein; Regulates arginine biosynthesis genes. | 0.412 |
| dacA | dnaX | HMPREF0501_01094 | HMPREF0501_01178 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.431 |
| dacA | glmM | HMPREF0501_01094 | HMPREF0501_01092 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.958 |
| dacA | glmS | HMPREF0501_01094 | HMPREF0501_01091 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.512 |
| dacA | mutS2 | HMPREF0501_01094 | HMPREF0501_00996 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | 0.643 |
| dacA | pgcA | HMPREF0501_01094 | HMPREF0501_01138 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Phosphoglucomutase. | 0.742 |