| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEU29610.1 | apt | HMPREF0501_01617 | HMPREF0501_00073 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.431 |
| EEU29610.1 | gmk | HMPREF0501_01617 | HMPREF0501_00421 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.565 |
| EEU29610.1 | guaA | HMPREF0501_01617 | HMPREF0501_01335 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| EEU29610.1 | guaC | HMPREF0501_01617 | HMPREF0501_01562 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.946 |
| EEU29610.1 | hpt | HMPREF0501_01617 | HMPREF0501_01428 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.943 |
| EEU29610.1 | pyrD | HMPREF0501_01617 | HMPREF0501_00383 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.607 |
| EEU29610.1 | pyrG | HMPREF0501_01617 | HMPREF0501_01407 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.576 |
| EEU29610.1 | xpt | HMPREF0501_01617 | HMPREF0501_00841 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.940 |
| EEU30345.1 | EEU30829.1 | HMPREF0501_00723 | HMPREF0501_00234 | Guanylate kinase. | Phosphoribosyl transferase domain protein. | 0.956 |
| EEU30345.1 | apt | HMPREF0501_00723 | HMPREF0501_00073 | Guanylate kinase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.959 |
| EEU30345.1 | gmk | HMPREF0501_00723 | HMPREF0501_00421 | Guanylate kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.948 |
| EEU30345.1 | guaA | HMPREF0501_00723 | HMPREF0501_01335 | Guanylate kinase. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.987 |
| EEU30345.1 | guaC | HMPREF0501_00723 | HMPREF0501_01562 | Guanylate kinase. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.937 |
| EEU30345.1 | hpt | HMPREF0501_00723 | HMPREF0501_01428 | Guanylate kinase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.942 |
| EEU30345.1 | xpt | HMPREF0501_00723 | HMPREF0501_00841 | Guanylate kinase. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.959 |
| EEU30829.1 | EEU30345.1 | HMPREF0501_00234 | HMPREF0501_00723 | Phosphoribosyl transferase domain protein. | Guanylate kinase. | 0.956 |
| EEU30829.1 | gmk | HMPREF0501_00234 | HMPREF0501_00421 | Phosphoribosyl transferase domain protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.955 |
| EEU30829.1 | guaA | HMPREF0501_00234 | HMPREF0501_01335 | Phosphoribosyl transferase domain protein. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.986 |
| EEU30829.1 | guaC | HMPREF0501_00234 | HMPREF0501_01562 | Phosphoribosyl transferase domain protein. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.940 |
| EEU30829.1 | hpt | HMPREF0501_00234 | HMPREF0501_01428 | Phosphoribosyl transferase domain protein. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.950 |