| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEU29610.1 | guaC | HMPREF0501_01617 | HMPREF0501_01562 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.946 |
| EEU29610.1 | hpt | HMPREF0501_01617 | HMPREF0501_01428 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.943 |
| EEU29610.1 | purA | HMPREF0501_01617 | HMPREF0501_01563 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.979 |
| EEU29610.1 | purB | HMPREF0501_01617 | HMPREF0501_01628 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.772 |
| EEU29610.1 | purH | HMPREF0501_01617 | HMPREF0501_01637 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Truncated CDS. | 0.966 |
| EEU29610.1 | tilS | HMPREF0501_01617 | HMPREF0501_01427 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | 0.428 |
| asnA | asnB | HMPREF0501_01369 | HMPREF0501_00099 | Aspartate--ammonia ligase. | Asparagine synthase (glutamine-hydrolyzing). | 0.947 |
| asnA | aspD | HMPREF0501_01369 | HMPREF0501_01223 | Aspartate--ammonia ligase. | Aspartate 4-decarboxylase. | 0.919 |
| asnA | purA | HMPREF0501_01369 | HMPREF0501_01563 | Aspartate--ammonia ligase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.932 |
| asnA | pyrB | HMPREF0501_01369 | HMPREF0501_00387 | Aspartate--ammonia ligase. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.932 |
| asnB | asnA | HMPREF0501_00099 | HMPREF0501_01369 | Asparagine synthase (glutamine-hydrolyzing). | Aspartate--ammonia ligase. | 0.947 |
| asnB | aspD | HMPREF0501_00099 | HMPREF0501_01223 | Asparagine synthase (glutamine-hydrolyzing). | Aspartate 4-decarboxylase. | 0.936 |
| asnB | purA | HMPREF0501_00099 | HMPREF0501_01563 | Asparagine synthase (glutamine-hydrolyzing). | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.948 |
| asnB | pyrB | HMPREF0501_00099 | HMPREF0501_00387 | Asparagine synthase (glutamine-hydrolyzing). | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.967 |
| aspD | asnA | HMPREF0501_01223 | HMPREF0501_01369 | Aspartate 4-decarboxylase. | Aspartate--ammonia ligase. | 0.919 |
| aspD | asnB | HMPREF0501_01223 | HMPREF0501_00099 | Aspartate 4-decarboxylase. | Asparagine synthase (glutamine-hydrolyzing). | 0.936 |
| aspD | purA | HMPREF0501_01223 | HMPREF0501_01563 | Aspartate 4-decarboxylase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.938 |
| aspD | pyrB | HMPREF0501_01223 | HMPREF0501_00387 | Aspartate 4-decarboxylase. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.934 |
| guaC | EEU29610.1 | HMPREF0501_01562 | HMPREF0501_01617 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.946 |
| guaC | hpt | HMPREF0501_01562 | HMPREF0501_01428 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.943 |