STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDExonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (374 aa)    
Predicted Functional Partners:
EEU29585.1
Exonuclease SbcCD, C subunit.
 
 0.999
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.994
dinG
Putative DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
  
 0.942
EEU30793.1
ATP-dependent DNA helicase, RecQ family.
  
 0.897
recQ
ATP-dependent DNA helicase RecQ.
  
 0.897
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.883
EEU30736.1
Putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase.
   
 
 0.770
budC
Diacetyl reductase ((R)-acetoin forming).
   
 
 0.770
EEU30520.1
Oxidoreductase, short chain dehydrogenase/reductase family protein.
   
 
 0.770
EEU30493.1
SNF2 family N-terminal domain protein.
  
 
 0.750
Your Current Organism:
Lactobacillus coleohominis
NCBI taxonomy Id: 575594
Other names: L. coleohominis 101-4-CHN, Lactobacillus coleohominis 101-4-CHN
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.