node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFI42127.1 | EFI42583.1 | HMPREF0629_00767 | HMPREF0629_01238 | UvrD/REP helicase. | Putative ATP-dependent DNA helicase PcrA. | 0.908 |
EFI42127.1 | dnaN | HMPREF0629_00767 | HMPREF0629_00309 | UvrD/REP helicase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.930 |
EFI42127.1 | mutL | HMPREF0629_00767 | HMPREF0629_00945 | UvrD/REP helicase. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.875 |
EFI42127.1 | mutS | HMPREF0629_00767 | HMPREF0629_00946 | UvrD/REP helicase. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.422 |
EFI42127.1 | polA | HMPREF0629_00767 | HMPREF0629_00614 | UvrD/REP helicase. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.833 |
EFI42127.1 | recA | HMPREF0629_00767 | HMPREF0629_00931 | UvrD/REP helicase. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.927 |
EFI42298.1 | miaA | HMPREF0629_00943 | HMPREF0629_00944 | Aluminum resistance protein. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.850 |
EFI42298.1 | miaB | HMPREF0629_00943 | HMPREF0629_00947 | Aluminum resistance protein. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.749 |
EFI42298.1 | mutL | HMPREF0629_00943 | HMPREF0629_00945 | Aluminum resistance protein. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.814 |
EFI42298.1 | mutS | HMPREF0629_00943 | HMPREF0629_00946 | Aluminum resistance protein. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.814 |
EFI42583.1 | EFI42127.1 | HMPREF0629_01238 | HMPREF0629_00767 | Putative ATP-dependent DNA helicase PcrA. | UvrD/REP helicase. | 0.908 |
EFI42583.1 | dnaN | HMPREF0629_01238 | HMPREF0629_00309 | Putative ATP-dependent DNA helicase PcrA. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.944 |
EFI42583.1 | mutL | HMPREF0629_01238 | HMPREF0629_00945 | Putative ATP-dependent DNA helicase PcrA. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.880 |
EFI42583.1 | mutS | HMPREF0629_01238 | HMPREF0629_00946 | Putative ATP-dependent DNA helicase PcrA. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.422 |
EFI42583.1 | polA | HMPREF0629_01238 | HMPREF0629_00614 | Putative ATP-dependent DNA helicase PcrA. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.833 |
EFI42583.1 | recA | HMPREF0629_01238 | HMPREF0629_00931 | Putative ATP-dependent DNA helicase PcrA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.939 |
EFI42678.1 | mutL | HMPREF0629_01340 | HMPREF0629_00945 | MutS domain V protein. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.792 |
EFI42678.1 | mutS | HMPREF0629_01340 | HMPREF0629_00946 | MutS domain V protein. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.652 |
EFI42678.1 | polA | HMPREF0629_01340 | HMPREF0629_00614 | MutS domain V protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.573 |
dnaN | EFI42127.1 | HMPREF0629_00309 | HMPREF0629_00767 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UvrD/REP helicase. | 0.930 |