node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
VS_0247 | VS_1344 | VS_0247 | VS_1344 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.862 |
VS_0247 | VS_1797 | VS_0247 | VS_1797 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.972 |
VS_0247 | VS_2249 | VS_0247 | VS_2249 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Citrate synthase; Belongs to the citrate synthase family. | 0.862 |
VS_0247 | VS_2569 | VS_0247 | VS_2569 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Oxaloacetate decarboxylase alpha chain. | 0.829 |
VS_0247 | fumC | VS_0247 | VS_2937 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.884 |
VS_0247 | mdh | VS_0247 | VS_0358 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.894 |
VS_0247 | pckA | VS_0247 | VS_0131 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.629 |
VS_0247 | sucC | VS_0247 | VS_2241 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.953 |
VS_0247 | sucD | VS_0247 | VS_2240 | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.972 |
VS_1071 | VS_1344 | VS_1071 | VS_1344 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.556 |
VS_1071 | VS_1797 | VS_1071 | VS_1797 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.506 |
VS_1071 | VS_2249 | VS_1071 | VS_2249 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. | Citrate synthase; Belongs to the citrate synthase family. | 0.559 |
VS_1071 | mdh | VS_1071 | VS_0358 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.954 |
VS_1071 | sucC | VS_1071 | VS_2241 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. | Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.534 |
VS_1071 | sucD | VS_1071 | VS_2240 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. | Succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.502 |
VS_1344 | VS_0247 | VS_1344 | VS_0247 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.862 |
VS_1344 | VS_1071 | VS_1344 | VS_1071 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. | 0.556 |
VS_1344 | VS_1797 | VS_1344 | VS_1797 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.962 |
VS_1344 | VS_2569 | VS_1344 | VS_2569 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Oxaloacetate decarboxylase alpha chain. | 0.855 |
VS_1344 | fumC | VS_1344 | VS_2937 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.789 |