152.t00023 protein (Entamoeba histolytica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

152.t00023

Protein kinase, putative. (401 aa)

Predicted Functional Partners:

203.t00013

0.654

163.t00014

0.651

151.t00003

0.625

rac1

0.463

223.t00001

0.460

3.t00144

0.457

4.t00078

0.457

203.t00017

0.457

115.t00011

0.437

NADK

0.421

Your Current Organism:

Entamoeba histolytica

NCBI taxonomy Id: 5759
Other names: E. histolytica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
115.t00011	151.t00003	C4M882	C4M0V4	Epimerase domain-containing protein.	Uncharacterized protein.	0.709
115.t00011	152.t00023	C4M882	C4LVH0	Epimerase domain-containing protein.	Protein kinase, putative.	0.437
115.t00011	163.t00014	C4M882	C4M7Y2	Epimerase domain-containing protein.	Eukaryotic translation elongation factor 1 gamma, putative.	0.701
115.t00011	203.t00013	C4M882	C4M079	Epimerase domain-containing protein.	Bacterial transferase hexapeptide family protein.	0.677
115.t00011	223.t00001	C4M882	C4LXD7	Epimerase domain-containing protein.	Fructose-1,6-bisphosphate aldolase, putative.	0.879
115.t00011	4.t00078	C4M882	C4M3D4	Epimerase domain-containing protein.	RNA-binding protein, putative.	0.831
151.t00003	115.t00011	C4M0V4	C4M882	Uncharacterized protein.	Epimerase domain-containing protein.	0.709
151.t00003	152.t00023	C4M0V4	C4LVH0	Uncharacterized protein.	Protein kinase, putative.	0.625
151.t00003	163.t00014	C4M0V4	C4M7Y2	Uncharacterized protein.	Eukaryotic translation elongation factor 1 gamma, putative.	0.836
151.t00003	203.t00013	C4M0V4	C4M079	Uncharacterized protein.	Bacterial transferase hexapeptide family protein.	0.841
151.t00003	223.t00001	C4M0V4	C4LXD7	Uncharacterized protein.	Fructose-1,6-bisphosphate aldolase, putative.	0.706
151.t00003	4.t00078	C4M0V4	C4M3D4	Uncharacterized protein.	RNA-binding protein, putative.	0.682
152.t00023	115.t00011	C4LVH0	C4M882	Protein kinase, putative.	Epimerase domain-containing protein.	0.437
152.t00023	151.t00003	C4LVH0	C4M0V4	Protein kinase, putative.	Uncharacterized protein.	0.625
152.t00023	163.t00014	C4LVH0	C4M7Y2	Protein kinase, putative.	Eukaryotic translation elongation factor 1 gamma, putative.	0.651
152.t00023	203.t00013	C4LVH0	C4M079	Protein kinase, putative.	Bacterial transferase hexapeptide family protein.	0.654
152.t00023	203.t00017	C4LVH0	Q8WQH7	Protein kinase, putative.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.457
152.t00023	223.t00001	C4LVH0	C4LXD7	Protein kinase, putative.	Fructose-1,6-bisphosphate aldolase, putative.	0.460
152.t00023	3.t00144	C4LVH0	B1N2G7	Protein kinase, putative.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.457
152.t00023	4.t00078	C4LVH0	C4M3D4	Protein kinase, putative.	RNA-binding protein, putative.	0.457