STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
24.t00009Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (884 aa)    
Predicted Functional Partners:
PGM
Phosphoglucomutase, putative; Belongs to the phosphohexose mutase family.
  
 
 0.991
77.t00009
Glycogen debranching enzyme, putative.
  
 0.991
106.t00014
UTP--glucose-1-phosphate uridylyltransferase.
   
 
 0.988
EHI_038160
1,4-alpha-glucan branching enzyme, putative.
  
 0.984
448.t00005
Starch branching enzyme, putative.
 
 0.984
1.t00098
4-alpha-glucanotransferase, putative.
 
 
 0.973
24.t00041
Alpha-amylase.
  
 0.966
409.t00002
Phosphoglucomutase/phosphomannomutase family protein; Belongs to the phosphohexose mutase family.
  
 
 0.960
35.t00052
Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
  
 
0.901
EHI_046900
4-alpha-glucanotransferase, putative.
 
 
 0.875
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.