STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
18.t00001Cullin, putative; Belongs to the cullin family. (741 aa)    
Predicted Functional Partners:
9.t00057
Ankyrin repeat/GTPase-activator domain containing protein.
    
 0.999
275.t00007
Uncharacterized protein.
   
 0.999
60.t00012
Putative transcription enhancer protein.
   
 0.928
2.t00108
RING finger protein, putative.
    
 0.864
95.t00014
Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
   
 0.850
GK
Glycerate kinase, putative.
   
 0.850
300.t00010
Ubiquitin-like, putative.
    
 0.848
EHI_152700
Uncharacterized protein; Belongs to the SKP1 family.
   
 0.837
98.t00007
Ubiquitin-conjugating enzyme family protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.807
14.t00031
Uncharacterized protein.
   
 0.804
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.