STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
144.t00012RuvB-like helicase; Belongs to the RuvB family. (439 aa)    
Predicted Functional Partners:
211.t00005
RuvB-like helicase; Belongs to the RuvB family.
  
0.999
3.t00067
Uncharacterized protein.
   
 0.996
48.t00008
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.994
29.t00037
Uncharacterized protein.
    
 0.987
528.t00002
SnoRNA binding protein, putative.
   
 
 0.986
25.t00034
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.972
39.t00045
Histone H2B; Belongs to the histone H2B family.
   
 0.961
8.t00057
Uncharacterized protein.
   
 0.944
254.t00012
Centromere/microtubule binding protein cbf5, putative.
   
 0.918
117.t00021
Histone H2A; Belongs to the histone H2A family.
    
 0.908
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.