STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
102.t00006Uncharacterized protein. (271 aa)    
Predicted Functional Partners:
78.t00035
Uncharacterized protein.
   
 0.999
221.t00013
Rho guanine nucleotide exchange factor, putative.
   
 0.999
84.t00019
Protein with RhoGEF and ArfGAP domains.
   
 0.999
7.t00076
Rho guanine nucleotide exchange factor, putative.
   
 0.999
101.t00009
Uncharacterized protein.
   
 0.937
1.t00001
Actin-like protein, putative.
   
 0.910
890.t00001
Actin-related protein 3, putative; Belongs to the actin family.
    
 0.890
211.t00012
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 0.844
118.t00012
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
   
 0.827
429.t00005
Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.
    
 0.822
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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