STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
63.t00025Uncharacterized protein. (1005 aa)    
Predicted Functional Partners:
109.t00007
Uncharacterized protein.
   
 0.978
HDAC
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.976
322.t00001
WD domain containing protein.
   
 0.946
472.t00010
WD domain containing protein.
   
 0.945
8.t00057
Uncharacterized protein.
    
 0.760
144.t00012
RuvB-like helicase; Belongs to the RuvB family.
   
 0.757
162.t00003
DNA-directed RNA polymerase II subunit, putative.
   
 0.757
51.t00031
DNA-directed RNA polymerases I, II, and III 23 kDa, putative.
  
 0.751
25.t00034
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.735
188.t00012
HMG box protein.
   
 0.704
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.