STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
7.t00075Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (171 aa)    
Predicted Functional Partners:
23.t00055
Prefoldin subunit 6, putative.
   
 0.999
298.t00014
Prefoldin subunit 2, putative.
   
 0.999
23.t00063
Prefoldin, alpha subunit.
   
 0.996
406.t00008
Prefoldin, alpha subunit.
   
 0.996
118.t00028
T-complex protein 1 beta subunit, putative.
   
 0.892
469.t00003
T-complex protein 1 subunit alpha, putative.
   
 0.820
23.t00046
Chaperonin containing TCP-1 epsilon subunit, putative.
   
 0.811
EHI_071600
T-complex protein 1 subunitTheta, putative.
   
 0.776
60.t00016
T-complex protein 1 theta subunit, putative.
   
 0.776
EHI_044940
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
   
 0.757
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.