STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
108.t00028Rho family GTPase. (194 aa)    
Predicted Functional Partners:
78.t00035
Uncharacterized protein.
    
 0.998
152.t00013
Uncharacterized protein.
   
 0.996
28.t00003
Guanine nucleotide exchange factor, putative.
    
 0.944
6.t00075
Protein kinase, putative.
   
 0.942
221.t00013
Rho guanine nucleotide exchange factor, putative.
   
 0.884
84.t00019
Protein with RhoGEF and ArfGAP domains.
   
 0.884
7.t00076
Rho guanine nucleotide exchange factor, putative.
    
 0.883
31.t00008
RhoGAP domain containing protein.
   
 0.807
233.t00022
RhoGAP domain containing protein.
   
 0.806
33.t00031
Uncharacterized protein.
    
 0.804
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.