STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
229.t00010Uncharacterized protein. (386 aa)    
Predicted Functional Partners:
EhRabX10
Small GTPase EhRabX10.
   
 
 0.847
15.t00012
Sulfate adenylyltransferase, putative.
   
  
 0.705
79.t00002
Sulfate adenylyltransferase, putative.
   
  
 0.695
129.t00014
Synapsin, putative.
   
 
 0.680
580.t00001
Syntaxin binding protein, putative; Belongs to the STXBP/unc-18/SEC1 family.
   
 
 0.627
62.t00003
Guanylate kinase, putative.
   
 
 0.624
443.t00007
Syntaxin, putative.
   
 
 0.588
9.t00010
Syntaxin PM-like protein.
   
 
 0.583
218.t00012
Syntaxin, putative.
     
 0.579
4.t00118
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]
   
 
 0.523
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.