STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
301.t00002SH3 domain-containing protein. (2166 aa)    
Predicted Functional Partners:
345.t00011
DNA replication licensing factor, putative; Belongs to the MCM family.
   
 0.891
4.t00027
Cell division control protein 45 CDC45, putative.
   
 0.840
18.t00056
DNA helicase; Belongs to the MCM family.
   
 0.802
40.t00023
DNA replication licensing factor, putative; Belongs to the MCM family.
   
 0.802
EHI_192770
Uncharacterized protein.
   
 0.781
464.t00003
Phosphatidylinositol 3-and 4-kinase family; Belongs to the PI3/PI4-kinase family.
   
 
 0.698
EHI_129730
Protein kinase rad3, putative; Belongs to the PI3/PI4-kinase family.
   
 
 0.695
141.t00006
Uncharacterized protein.
   
 
 0.688
85.t00006
DNA replication licensing factor MCM3; Belongs to the MCM family.
   
 0.614
62.t00007
DNA helicase; Belongs to the MCM family.
   
 0.580
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.