STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
366.t00008Uncharacterized protein. (244 aa)    
Predicted Functional Partners:
46.t00053
Protein kinase domain containing protein.
   
 0.864
67.t00005
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.864
HDAC
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 
 0.731
200.t00017
Heat shock transcription factor, putative.
   
 
 0.690
130.t00015
Bromodomain protein, putative.
    
 
 0.611
58.t00022
Uncharacterized protein.
    
 0.577
520.t00002
DNA polymerase, putative.
    
 0.577
EHI_050580
Uncharacterized protein.
   
 
 0.513
114.t00009
Serine/threonine-protein kinase PLK.
    
 
 0.500
169.t00013
Phosphoribulokinase /uridine kinase family protein.
   
 
 0.468
Your Current Organism:
Entamoeba histolytica
NCBI taxonomy Id: 5759
Other names: E. histolytica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.